Abstract

SEGOVIA VAZQUEZ, María Raquel. Acute pneumonia associated influenza-like illness in pregnant and nonpregnant in Itauguá National Hospital, Paraguay. Rev. Nac. (Itauguá) [online]. 2011, vol.3, n.2, pp.16-22. ISSN 2072-8174.

ABSTRACT Introduction: The emergence and global spread of the new strain of influenza virus A H1 N1 has resulted in the first pandemic of the century. Pregnant women are at higher risk for severe disease and complications from influenza A H1N1. Objective: To determine the proportion of community acquired pneumonia associated with influenza-like illness in pregnant and non pregnant woman and compare the clinical characteristics and outcome in both groups of patients admitted to the National Hospital. Material and methods: A retrospective cohort design which compared 67 pregnant with 27 non-pregnant with community acquired pneumonia , admited to the Hospital during the pandemic pediod from July to September 2009. Results: The proportion of pregnant women with community acquired pneumonia was 67 (71.2%) and 27 non-pregnant women (28.7%), the average age of both groups was 27 ± 10 years. Non-pregnant women had a higher respiratory rate 27 ± 4 vs. 24 ± 5 (p = 0.01, t test). Results of hemogram and O2 saturation did not differ. In lung semiology Pregnant women had more wheezing 16 (23.8%) vs. 12 (44.4%) (RR = 0.38 95% CI 0.22 to 0.66 p = 0.02), crepts 28 (41.8%) vs. 15 (55.5%) (RR = 0.62 95% p = 0.01) and rhonchi 13 (19.4%) vs. 8 (29.6%) (RR = 0.2 95% CI 0.2 to 1.07 p = 0.08). The predominant lung involvement was bilateral in both cohorts. Required admission to ICU 25 (27%) of both cohort, pregnant 16 (23.9%), no pregnant 9 (33.3%), mortality in the pregnant group was 6 (8.9%) vs. 5 (18.5%) in non-pregnant women. Conclusion: The frequency of hospitalization in community acquired pneumonia associated with influenza-like illness was higher in pregnant women, clinical features and outcome were similar in both groups and the overall mortality was 11.7%.

Keywords : Keywords: influenza A virus, human influenza, orthomyxoviridae, pregnancy, Paraguay.

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