Abstract

SAMUDIO-DOMINGUEZ, Gloria Celeste; PANIAGUA, Jessica Pamela; SOLUODRE, Stephany  and  ORTIZ-CUQUEJO, Lidia María. Seroprevalence study of HVS 1-2 in pregnant people and newborn from 2017 to 2021. Rev. Inst. Med. Trop. [online]. 2023, vol.18, n.2, pp.4-10. ISSN 1996-3696.  https://doi.org/10.18004/imt/2023.18.2.2.

The herpes simplex virus (HSV) belongs to the alpha virus subfamily, a member of the family Herpes viridae. There are two closely related types of HSV, HSV type 1 and HSV-2, which cause diseases of varying severity. HSV-1 is transmitted mainly by mouth-to-mouth contact and HSV-2 is transmitted sexually, both of which can cause genital herpes. The global burden of morbidity and mortality from sexually transmitted pathogens compromises life, as well as sexual and reproductive health, and the health of the newborn. Objective: To determine the IgG and IgM seroprevalence for HSV 1 - 2 of newborns and mothers in the period from January 2017 to July 2021 in a third level hospital. Materials and Methods: Observational, retrospective, cross-sectional study of January 2017 to July 2021. IgG and IgM antibodies were measured in newborns and pregnant women in the last trimester, using the ELISA method. Results: Of a total of 4712 IgG and IgM serologies of mothers and newborns analyzed the seroprevalence of IgG in pregnant women was close to 100% with similar value in newborns (87%), IgM seroprevalence in mothers was 0.23% and the RN 0.36% with an upward trend. Conclusion: The IgG seroprevalence for HSV is high, while the IgM seroprevalence in pregnant women and newborns during the study period is significantly low.

Keywords : seroprevalence; newly born; pregnant; herpes simplex virus 1 and 2.

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