Abstract

VILLAR, Gustavo; BENITEZ, Gustavo; VILLALBA, Joaquín  and  ALMIRON, Desirée. Invasive disease by Streptococcus pneumoniae, in adult patients. Period 2016 to 2018. Rev. Inst. Med. Trop. [online]. 2022, vol.17, n.2, pp.37-43. ISSN 1996-3696.  https://doi.org/10.18004/imt/2022.17.2.5.

Introduction: In Paraguay and in other parts of the world, Streptococcus pneumoniae is the main causative agent of bacterial pneumonia, otitis media, meningitis and septicemia. Objective: To describe the clinical-epidemiological characteristics of patients with invasive disease due to Streptococcus pneumoniae treated at the Institute of Tropical Medicine (IMT) during the years 2016 to 2019. Methodology: Observational, descriptive, cross-sectional study. All patients with confirmed invasive disease due to Streptococcus pneumoniae were included. Results: 34 patients were included, the average age was 44 years, 76% were male, 61% diagnosed with HIV infection. The predominant infectious focus was the lung. Of the biological samples with positive cultures, 73% were isolated from blood, and the rest distributed among samples of sputum, cerebrospinal fluid, and pleural fluid. 24% of the patients presented complications, between organic failure (15%) and empyema (9%). 59% of the patients received treatment with cephalosporins. The registered intrahospital mortality was 18%. Conclusion: The patients with invasive disease who attended the IMT during the years 2016 to 2019 were mostly young adults, immunosuppressed, with pneumonia.

Keywords : Streptococcus pneumoniae; Pneumococcal Infections; Meningitis; Pneumococcal; Pneumonia; Pneumococcal.

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