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Anales de la Facultad de Ciencias Médicas (Asunción)

Print version ISSN 1816-8949


GARCETE MANOTTI, Lidia et al. Enzyme replacement treatment in exocrine pancreatic insufficiency associated with cystic fibrosis. Cystic fibrosis Working group of the Latin American Society of Pediatric Gastroenterology, Hepatology and Nutrition (LASPHGAN). An. Fac. Cienc. Méd. (Asunción) [online]. 2022, vol.55, n.3, pp.76-85. ISSN 1816-8949.

Cystic fibrosis (CF) is an inherited disorder of the exocrine secretion glands, considered the most frequent cause of exocrine pancreatic insufficiency (EPI) in childhood. This review summarizes the landscape of enzyme replacement therapy in PEI associated with CF, the available formulations, their dosage and mode of administration, as well as the current limitations and challenges and potential areas for future development.

Keywords : cystic fibrosis; exocrine pancreatic insufficiency; malabsorption; enzyme replacement..

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