Abstract

SANDOVAL, José Hernando; INSFRAN, Wilson Nicolás  and  ALDANA, Celso Augusto. Verruciform epidermodysplasia and epidermoid carcinoma - diagnosis and treatment. An. Fac. Cienc. Méd. (Asunción) [online]. 2020, vol.53, n.3, pp.165-172. ISSN 1816-8949.  https://doi.org/10.18004/anales/2020.053.03.165.

Verruciform epidermodysplasia is a rare, autosomal recessive precancerous genodermatosis with a worldwide distribution. Carriers of this disease present a selective cellular immunosuppression against certain types of human papilloma virus, especially with genotypes 5 and 8, developing from early ages of life lesions similar to pityriasis versicolor, flat warts and seborrheic keratoses, very widespread, chronic and refractory to treatment. Multiple squamous cell carcinomas are common, especially in the context of carcinogenic cofactors such as the sun. We present a patient with a diagnosis of verruciform epidermodysplasia, who evidenced flat wart-like lesions, seborrheic keratoses and squamous carcinoma, which was treated with excision with a margin of safety and reconstruction with partial skin graft and placement of a vacuum-sealed aspiration system with good evolution.

Keywords : warts; squamous cell carcinoma; cutaneous neoplasms..

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