Ground and objective:

On this preliminary study we aim to determine the demographic features and the relation between certain risk factors and the presence of Gram negative betalactamase producing bacteria (ESBL) in urinary tract infections (UTI) on hospitalized patients.

Materials and Methods:

An observational, retrospective, cross sectional, case control type study was performed; on adult patients of both genders that were hospitalized in the Internal Medicine wards from Hospital de Clínicas, in the city of San Lorenzo, from January 2015 to August 2017, that had positive urine culture for Gram negative bacteria, and its relationship with diverse factors.

Results:

Escherichia Coli was isolated on 43% of nosocomial UTI, followed by Klebsiella pneumoniae (32%), Pseudomona aeruginosa (9%), Enterobacter cloacae (4%), Proteus mirabilis (4%), Morganella morganii (2%). As for the risk factors associated to nosocomial UTI produced by Gram negative ESBL-producing bacteria, the prior use of antibiotics was the greatest associated factor with an OR 2,5 (CI 95% 2,5-21,8) p 0,001.

Conclusion:

The most implicated Gram negative bacteria on nosocomial UTI was Escherichia Coli. The greatest percentage of patients that presented nosocomial UTI during their admission belonged to female sex, presented comorbidities and was hospitalized for a period longer than 10 days. As to the associated risk factors for nosocomial UTI produced by Gram negative ESBL-producing bacteria, the prior use of antibiotics was the greatest associated factor.

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