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Anales de la Facultad de Ciencias Médicas (Asunción)

Print version ISSN 1816-8949


FLORES, J  and  FACULTAD DE CIENCIAS MEDICAS, UNIVERSIDAD NACIONAL DE ASUNCION. Primera Cátedra y Servicio de Clínica Quirúrgica. 2 Hemocentro del Hospital de Clínicas. 3 Departamento de Hematología et al. Stem cells in the treatment of lower limb ischemia. First case in Paraguay and our experience in the Hospital of the National University of Asunción. An. Fac. Cienc. Méd. (Asunción) [online]. 2015, vol.48, n.2, pp.59-66. ISSN 1816-8949.

ABSTRACT There is a group of patients with critical limb ischemia, whom are not adequate for surgical or endovascular revascularization. They present a high risk of amputation. In last decades, it has been identified a group of bone marrow CD34+ stem cells, that proliferate in case of tissue ischemia, migrate through the circulation to the ischemic tissue and originate new vessels. This event is complicated in vivo by the occlusion of arteries of the affected region. In this paper, we present our experience in two patients, who underwent harvesting of their bone marrow tissue, which has been strained and then sowed in the ischemic lower limb to develop new blood vessels, thus improving blood flow to this area and wound healing, avoiding lower limb amputation. Key Words: Critical ischemia, arterial revascularization, stems cells

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