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Memorias del Instituto de Investigaciones en Ciencias de la Salud

versão On-line ISSN 1812-9528


PEREZ-BEJARANO, Domingo. Combined pulmonary fibrosis and emphysema syndrome: dawn of antifibrotic treatment in Paraguay. Mem. Inst. Investig. Cienc. Salud [online]. 2022, vol.20, n.3, pp.148-154. ISSN 1812-9528.

The concomitance of pulmonary fibrosis in the lower regions of the lung and emphysema in the upper lobes characterize a rare entity called combined pulmonary fibrosis and emphysema syndrome, which is usually associated with a high burden of smoking, although other associations have been described and which carries a poor prognosis. Pulmonary hypertension, lung cancer, and acute exacerbation are possible complications. In the context of a multidisciplinary approach to the management of three cases, we report the course of treatment with pirfenidone.

Palavras-chave : Combination of pulmonary fibrosis and emphysema; pulmonary emphysema; pulmonary fibrosis; smoking; pulmonary hypertension.

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