SciELO - Scientific Electronic Library Online

vol.20 número2Analysis of the Excess Demand of the Barrio Obrero General Hospital. Organizational and functional implications of an urban micronetwork. Asunción, Paraguay 2018-2019Evaluation of primers reported for KDR detection in Anopheles species collected in the departments of Caaguazú and Alto Paraná in Paraguay índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados




  • Não possue artigos citadosCitado por SciELO

Links relacionados

  • Não possue artigos similaresSimilares em SciELO


Memorias del Instituto de Investigaciones en Ciencias de la Salud

versão On-line ISSN 1812-9528


FALCON, Myrian et al. Surveillance of antimicrobial resistance in strains of Neisseria gonorrhoeae isolated in Paraguay. Year 2021. Mem. Inst. Investig. Cienc. Salud [online]. 2022, vol.20, n.2, pp.20-28. ISSN 1812-9528.

Neisseria gonorrhoeae (N. gonorrhoeae) is the causal agent of gonorrhea, a sexually transmitted infection (STI) that is the second most common cause of STIs worldwide, causing high morbidity and cost in health care. In recent decades, reports of strains resistant to penicillin, fluoroquinolones, sulfonamides, tetracycline, macrolides, and more recently to azithromycin and extended-spectrum cephalosporins such as ceftriaxone and cefixime have increased worldwide. The main objective of this study was to determine the sensitivity to antimicrobials in N. gonorrhoeae strains that were sent to the Central Laboratory of Public Health (LCSP), by the collaborating centers of the Antimicrobial Resistance Laboratory Surveillance Network (RAM). For this, a prospective cross-sectional study was carried out from January to December, 2021. One hundred eighty strains were characterized as N. gonorrhoeae, which were subjected to sensitivity tests, obtaining 48% resistance and 52% intermediate sensitivity to penicillin while 70% presented resistance to ciprofloxacin and 19% to tetracycline. Also, 100% sensitivity to ceftriaxone and cefixime was obtained. The most prevalent resistance phenotype was QRNG, associated with resistance to ciprofloxacin, followed by the PPNG-QRNG phenotype, associated with resistance to penicillin and ciprofloxacin. Given these findings and the global emergence of antimicrobial resistance, especially extended-spectrum cephalosporins, it is recommended that bacteriology laboratories fortify surveillance to support case detection and provide appropriate treatment.

Palavras-chave : N. gonorrhoeae; antimicrobial resistance; surveillance.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )