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Memorias del Instituto de Investigaciones en Ciencias de la Salud

versión On-line ISSN 1812-9528

Resumen

TOLEDO, Justino; DENIS, Rita  y  ORTIZ GALEANO, Ignacio. Frequency and clinicopathological characteristics of obese women with breast cancer in the Oncology Department of the Hospital de Clínicas. Mem. Inst. Investig. Cienc. Salud [online]. 2021, vol.19, n.1, pp.58-63. ISSN 1812-9528.  https://doi.org/10.18004/mem.iics/1812-9528/2021.019.01.58.

Given the increase in obesity in recent years, an increase is observed not only in cardiovascular risk factors, but also in the incidence of cancer due to its known participation in oncogenesis processes. The objective of the study was to determine the frequency and clinicopathological characteristics of obese women diagnosed with breast cancer in the Oncology service of the Hospital de Clínicas. Observational, descriptive, retrospective cross-sectional design, which included patients with a diagnosis of breast cancer from the Oncology Service of the Hospital de Clínicas from January 2017 to June 2019. Demographic variables, body mass index, histological subtype, presence of hormone receptors and overexpression of the HER 2neu oncogene were determined. One hundred forty four subjects were analyzed, the mean age was 52 ± 12.2 years, and the most frequent origin was from cities of the central department (54%). Forty point two percent was obese and 36.8% was overweight at the time of diagnosis. The most frequent histological subtype found in overweight and obese women was ductal carcinoma (81.9%), and 78.3% had positive hormone receptors to immunohistochemistry and overexpression of the HER 2 neu oncogene was found in 11.7%. The frequency of obesity in women diagnosed with breast cancer in the Oncology service of the Hospital de Clínicas was high. The most frequent anatomopathological characteristics were infiltrating ductal carcinoma, biological data show estrogen and / or progesterone receptors to a greater extent and overexpression of the HER 2 neu oncogene in the smallest part of the cases.

Palabras clave : breast cancer; overweight; obesity.

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