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Memorias del Instituto de Investigaciones en Ciencias de la Salud

On-line version ISSN 1812-9528

Abstract

VAZQUEZ, Marcos Aurelio et al. Characteristics clinical-epidemiological of the patients of the Lupus Paraguay cohort (2013-2014). Mem. Inst. Investig. Cienc. Salud [online]. 2019, vol.17, n.1, pp.69-74. ISSN 1812-9528.  http://dx.doi.org/10.18004/mem.iics/1812-9528/2019.017(01)69-074.

Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology that presents severe clinical manifestations and unpredictable course. It has been observed in several cohorts that this disease has a more aggressive behavior in the non-Caucasian population due to socioeconomic, demographic and genetic differences. The objective of this study was to describe the clinical-epidemiological characteristics of SLE patients included in the LUPUS-PY cohort and the current situation of the samples stored in the BIOBANCO IMID-PY. The study was based on the review of clinical histories and clinical-epidemiological questionnaires on the day of inclusion in the LUPUS-PY registry. Frequencies were calculated for the categorical variables and the means with their standard deviation for the continuous ones. A total of 83 patients with a diagnosis of SLE were included consecutively (mean age: 34.4 ± 10.0 years), 86.7% were female, 55% were from Asunción, 49.1% had basic education level, 45% received monthly a minimum salary (approximately 350 US dollars) or less. Forty six point eight percent did not perform any type of physical activity. The mean time elapsed since the onset of symptoms and the diagnosis of SLE was 9.3 ± 13.7 years, and the time of evolution of the disease until entry into the registry was 5.9 ± 6.3. Sixteen percent reported a family history of autoimmune diseases. The first manifestation of the disease more described was articular. Patients with SLE in our center have both clinical and epidemiological characteristics similar to those reported by other cohorts.

Keywords : systemic lupus erythematosus; LUPUS-PY registry; clinical and epidemiological characteristics.

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