Abstract

LEGUIZAMON, Myrian; SAMUDIO, Margarita  and  AGUILAR, Gustavo. Antimicrobial susceptibility of isolated enterobacteria in urinary tract infections of ambulatory and hospitalized patients of Hospital Central IPS. Mem. Inst. Investig. Cienc. Salud [online]. 2017, vol.15, n.3, pp.41-49. ISSN 1812-9528.  https://doi.org/10.18004/mem.iics/1812-9528/2017.015(03)41-049.

The objective of this descriptive, retrospective and cross-sectional study was to determine the sensitivity to antimicrobials of the enterobacteria obtained from the urine cultures from the Hospital Central of Instituto de Previsión Social (IPS) and to compare the sensitivity rate among species and origin of the samples. Clinical charts of ambulatory and hospitalized patients diagnosed with urinary infection at the Central Hospital of IPS from March 2015 to August 2016were retrospectively reviewed. Out of 4014 enterobacteria isolates as cause of urinary infection included, 3224 (80.3%) were from ambulatory samples and 790 (19.7%) from hospitalized patients. The most frequent uropathogen was Escherichiacoli (70, 1%) followed by Klebsiella pneumoniae (18,9%), Enterobacter cloacae (2,8%) and other species(8,2%). The sensitivity of E. coli to fosfomicin, nitrofuranto in and aminoglycosides was high. Extended spectrum betalactamase (ESBL) was found in 24.4% of E. coli and 50,3% of K. pneumoniae. E. coli continues to be the most frequent cause of urinary tract infections. The recommended treatment of choice is fosfomicin, nitrofuranto in or aminoglycosides, as this scheme will cover more than 90% of the pathogens that cause urinary tract infection in the hospital of IPS. Enterobacteria producing atypical urinary infection should be investigated.

Keywords : urinary tract infections; antibiotic therapy; Enterobacteria; Paraguay.

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