Abstract

FLEITAS MENDOZA, EE; ORTIZ OVELAR, C; FERREIRA GAONA, MI  and  DIAZ REISSNER, CV. Caracterización epidemiológica del dengue en la Unidad de Terapia Intensiva Adultos. Hospital Central "Dr. Emilio Cubas" del Instituto de Previsión Social, Paraguay: Epidemiological characterization of dengue in the "Dr. Emilio Cubas" Adult Intensive Care Unit. Central Hospital of the Social Security Institute, Paraguay. Mem. Inst. Investig. Cienc. Salud [online]. 2015, vol.13, n.1, pp.31-40. ISSN 1812-9528.  https://doi.org/10.18004/Mem.iics/1812-9528/2015.013(01)31-040.

Dengue is a self-limiting systemic viral infection transmitted by mosquitoes. In the past 50 years, the incidence increased 30 times worldwide, with the circulation of the four viral serotypes. Paraguay has favourable socio-environmental conditions for its transmission, which may affect the availability of resources for the management of severe cases. The objective of this study was to determine the frequency of dengue in the Adult Intensive Care Unit (AICU) of the Central Hospital of the Social Security Institute from June 2011 to June 2013. It is a cross-sectional descriptive, observational study. Of 1,991 patients admitted to AICU, in 103 (5.2%) dengue was confirmed by clinical and laboratory findings. Median age was 47 years, 72.7% was female and 53.4% resided in Asuncion. The median of time until the first consultation was 2 days. The most common clinical manifestation was fever (87.4%), 65.1% presented bleeding and in this group 52.2% required hemoderivative transfusion. The medians of APACHE II and SOFA scores were 10 and 5, respectively. Half of the patients had at least one coexistent clinical condition. The NS1 test request was in average on 3±1 days, and IgG/IgM on 6±2 days; 64.1% of the cases were severe and 73.8% of these had complications. Median of days of hospitalization was 4 days. Despite the low frequency of dengue in the unit, its relevance is due to the high morbidity and mortality observed in these patients.

Keywords : severe dengue; epidemiology; intensive care.

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