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Memorias del Instituto de Investigaciones en Ciencias de la Salud

On-line version ISSN 1812-9528


ACOSTA, N  and  LOPEZ, E. Cepas de Trypanosoma cruzi en el Paraguay: Trypanosoma cruzi strains in Paraguay. Mem. Inst. Investig. Cienc. Salud [online]. 2013, vol.11, n.2, pp.78-89. ISSN 1812-9528.

Trypanosoma cruzi populations circulating in Paraguay have shown a great genetic diversity, which has been evaluated by different methodologies and techniques. Several genotypes of this parasite have been identified infecting a diversity of hosts, including patients, triatomines and wild and domestic animals from different regions. The genetic diversity observed in the isolates of our country could imply differences in the clinical manifestations of Chagas disease, as well as differences in their biological characteristics such as grade of infectivity, virulence, pathogenicity, antigenic capacity and susceptibility or resistance to trypanocidal drugs. Up to now, these aspects have been little explored and evaluated in Paraguayan strains. The isolation and identification of T. cruzi groups and subgroups that circulate in the different transmission cycles in a determined geographic region are still relevant because they allow knowing the dynamics of parasite transmission and evaluating the introduction risk from wild foci.

Keywords : Trypanosoma cruzi strains; Chagas disease; Paraguay.

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