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Memorias del Instituto de Investigaciones en Ciencias de la Salud

On-line version ISSN 1812-9528


SANABRIA, R et al. Clostridium perfringens:etiologic agent of infectious keratitis. Mem. Inst. Investig. Cienc. Salud [online]. 2005, vol.3, n.1, pp.74-75. ISSN 1812-9528.

Clostridium perfringens is a rare cause of infectious keratitis and usually produces severe necrotizing diseases. Case report: A 32 years old, male farmer from General Artigas, Paraguay consulted because of a history of trauma in the right eye, with a metal wire and was treated by cyclopegic NSAIDs (non-steroid anti-inflammatory) and therapeutic contact lenses for 18 days with no improvement He consulted to Ophthalmology Department of the National University of Asunción. The patient presented absence of light perception, chemosis, hypopyon and a deep central corneal defect (5 mm). Samples were collected by corneal scraping and Gram positive rods were revealed by direct examination. The culture was performed on sheep blood agar plate, chocolate agar plate and thioglycolate medium broth, incubated at 35°C. After laboratory results, the patient was treated with topic cefazolin (50 mg/ml) and gentamycin (14mg/ml) every hour. Clostridium perfringens grew in the thioglycolate medium broth after three days. Unfortunately, the patient did not return for control.

Keywords : Clostridium perfringens; Keratitis; Ophthalmology.

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