Introduction:

Juvenile systemic lupus erythematosus (JSLE) is a multisystem autoimmune disease characterized by the production of autoantibodies and the frequent development of immune complex-mediated glomerulonephritis. Lupus nephritis is a frequent and serious complication of JSLE, has a high associated morbidity rate, and is the cause of end-stage renal failure in many of these patients. IgA Nephropathy represents the most common etiology in the general population and is rarely associated with JSLE.

Clinical case:

a female adolescent with JSLE who was diagnosed with non-lupus nephritis (IgA nephropathy).

Conclusions:

The anatomopathological diagnosis is key to establish the prognosis and plan the treatment.

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