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Pediatría (Asunción)

On-line version ISSN 1683-9803


BERNAL VEGA, Erica Eliana et al. Clinical and laboratory characterization of pediatric patients with dengue without warning signs in a reference hospital in Paraguay. Pediatr. (Asunción) [online]. 2021, vol.48, n.2, pp.127-132. ISSN 1683-9803.


Dengue virus is transmitted by the bite of female Aedes aegypti mosquitoes. In Paraguay it is an endemic disease, with epidemics every 3-5 years, and with different types of presentation, from asymptomatic to severe forms, which can even trigger death.


To describe the clinical and laboratory characteristics of pediatric patients with a diagnosis of Dengue without warning signs who presented to the Pediatric Emergency Department of the Hospital de Clínicas of San Lorenzo, Paraguay, between November 2019 and March 2020.

Materials and Methods:

this was a descriptive, observational, retrospective, cross-sectional study of consecutive cases. Patients from 1 month to 18 years of age were included in a non-probability sampling.


221 patients were included. An average age of 8.6 years was obtained, with 51% being female. Regarding the symptoms, 100% of the patients manifested the presence of fever, followed in frequency by headache (45%), body pain (36%) and vomiting (18%). NS1 antigen detection analysis was performed in 107 patients, of which 75 were positive.


A similar gender distribution was observed, with a median age of 8 years. The most frequent clinical manifestations were fever, headache, and body pain; however, a higher frequency of patients with gastrointestinal symptoms was recorded compared to outbreaks in previous years, probably related to the circulating serotype. The NS1 antigen test was 70% positive.

Keywords : Dengue fever; epidemiology; Paraguay.

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