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Pediatría (Asunción)

versión On-line ISSN 1683-9803


MARTINEZ DE CUELLAR, Celia et al. Tuberculosis: Risk factors associated with mortality in patients ≤19 years hospitalized at the Institute of Tropical Medicine. Pediatr. (Asunción) [online]. 2019, vol.46, n.2, pp.77-81. ISSN 1683-9803.


The World Health Organization estimates that 10 million new cases of Tuberculosis (TB) occur annually in the world, of which 10% occur in children <15 years of age. Difficulties in accessing health facilities and delaying in the diagnosis and treatment increase mortality in childhood.


to evaluate the clinical and laboratory characteristics and factors associated with mortality in patients < 19 years of age who were hospitalized for TB at the Institute of Tropical Medicine.

Materials and Methods:

this was a descriptive, retrospective, observational study. We included hospitalized patients diagnosed with TB during the years 2010 to 2018. The data were obtained from the Hospital Epidemiology Department's database. The variables were demographic data, clinical presentation, diagnosis, treatment and factors associated with mortality. Descriptive and analytical analysis was performed. Alpha error was considered <5%. 98.


patients (pts) ≤19 years old were identified, with a mean age of 9.3 ± 6.3 years, 65.3% were male. 34.6% had human immunodeficiency virus infection, and 23.4% (23/98) had malnutrition; 42.4% lived in areas with a population with <100,000 inhabitants and 23.4% belonged to native people groups. 19.4% (19/98) died. Mortality was associated with living in areas with a population with <100,000 inhabitants (33.3% vs. 8.9%, p = 0.02. RR = 2.3. CI 1.1 - 5.0). Mortality was higher in meningeal tuberculosis presentations (46.2% vs. 15.3%, p <0.01. RR = 3.0; CI 1.4 - 6.5).


Tuberculosis predominated in males, more than 80% presented with comorbidities. Mortality was high and was associated with living in areas with <100,000 inhabitants and TB meningeal form.

Palabras clave : Tuberculosis; mortality; HIV.

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