SciELO - Scientific Electronic Library Online

 
vol.43 número3 índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

  • Não possue artigos citadosCitado por SciELO

Links relacionados

  • Não possue artigos similaresSimilares em SciELO

Compartilhar


Pediatría (Asunción)

versão On-line ISSN 1683-9803

Resumo

OMAR EUGENIO, Naveda Romero  e  NAVEDA MELENDEZ, Andrea Fabiola. Risk factors for the development of acute respiratory distress syndrome: a case-control study. Pediatr. (Asunción) [online]. 2016, vol.43, n.3, pp.225-231. ISSN 1683-9803.  https://doi.org/10.18004/ped.2016.diciembre.225-231.

Introduction:

The acute respiratory distress syndrome (ARDS) is an important cause of acute respiratory failure, is associated with a significant risk of mortality; despite current progress in mechanical ventilation and protective lung ventilation.

Objective:

Determine risk factors for the development of ARDS in children with more than 48 hours of mechanical ventilation.

Materials and Methods:

Was designed a case-control study, where were compared 61 children with ARDS with 183 controls without ARDS with age between 1 month and 15 years. A logistic regression model was created to evaluate the effect on the risk.

Results:

In univariate analysis, the factors associated with ARDS were: PELOD score, pulmonary contusion, multiple trauma, shock, red blood cell transfusion, fluid overload, PaO2/FiO2 ratio, oxygenation index, PEEP and pH. Through binary logistic regression was identified as predictors for the development of ARDS: More than 3 red blood cell transfusions (OR: 1.5; 95% CI 1.2 - 1.9, p = 0.010), fluid overload (OR: 1.3; 95% CI 1.1 - 5.7, p = 0.012) and oxygenation index more than 8 without other criteria for ARDS (OR: 1.9; 95% CI 1.4 - 2.6, p < 0.0001). Mortality was higher in the group with ARDS (37.7% vs. 6.0%, p < 0.0001).

Conclusion:

More than 3 red blood cell transfusions, fluid overload and oxygenation index more than 8 are risk factors for the development of ARDS. Early recognition of risk factors of ARDS could help decrease its development.

Palavras-chave : Acute respiratory distress syndrome; risk factors; children..

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )