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Pediatría (Asunción)

On-line version ISSN 1683-9803


RAMIREZ, Leticia et al. Vitamin D levels and cardiometabolic risk factors in a pediatric population. Pediatr. (Asunción) [online]. 2015, vol.42, n.3, pp.192-197. ISSN 1683-9803.

Introduction: In recent years it has been observed that low levels of vitamin D may influence the development of cardiovascular disease in the future. Objective: To examine the association between serum vitamin D levels and risk factors for cardiovascular disease and metabolic syndrome in a pediatric population. Materials and Methods: We performed an observational, descriptive study with an analytical component in 209 patients in whom we measured serum levels of 25-hydroxy-vitamin D (25 [OH] D) and evaluated their cardiovascular risk factors according to the criteria of the amended Adult Treatment Panel III (ATP III). Each group was compared using Student’s t-test. A value of p <0.05 for two-tailed tests was considered significant. Results: The average value of 25 (OH) D was 34,9ng / mL. The mean levels of 25 (OH) D was lower in the subgroup of patients with cardiovascular risk factors, namely: abdominal obesity, high blood pressure, elevated fasting blood glucose, low HDL-cholesterol levels and high triglycerides, however this difference was not statistically significant. Conclusion: Patients with cardiovascular risk factors had lower levels of vitamin D, however the difference was not statistically significant. Further studies are needed to determine whether low levels of vitamin D during childhood and adolescence may impact on the subsequent development of cardiovascular disease in adulthood.

Keywords : Vitamin D; cardiovascular disease; metabolic syndrome; children.

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