Abstract

SAMUDIO-DOMINGUEZ, Gloria Celeste et al. Sensitivity Patterns of Community-acquired Staphylococcus aureus Isolated from Skin and Soft Tissue in Children. Pediatr. (Asunción) [online]. 2015, vol.42, n.1, pp.31-36. ISSN 1683-9803.  https://doi.org/10.18004/ped.2015.abril.31-36.

Introduction: In recent decades Staphylococcus aureus has significantly changed its sensitivity to oxacillin in a number of countries.  Reports of resistance have increased in Paraguay, making adequate knowledge of trends in antimicrobial resistance patterns vital, as delayed initiation of appropriate and adequate therapy is associated with greater morbidity and mortality. Objective: To report the resistance profile of S. aureus in the population of children seen at the Hospital General de Barrio Obrero, Paraguay.   Materials and Methods: We conducted a cross-sectional observational and descriptive study of non-invasive samples taken from children between January 2012 and July 2013. The automated Vitek2 Compact (bioMerieux) was used for identification and the antibiogram.  Results: We isolated 79 strains in samples taken from purulent discharge from children aged 0 to 16. Resistance was found to oxacillin in 70%, to clindamycin in 21%, and inducible resistance to clindamycin in 14%. Sensitivity was 100% or near 100% for ciprofloxacin, rifampin, trimethoprim, levofloxacin, and tetracycline, the highest minimum inhibitory concentration for vancomycin was less than 1.Conclusion: The high resistance of S. aureus to oxacillin in our hospital makes the use of alternative drugs such as clindamycin or others obligatory in empirical therapy.

Keywords : Staphylococcus aureus; non-invasive samples; oxacillin; resistance.

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