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Pediatría (Asunción)

versão On-line ISSN 1683-9803


MIR, R et al. High-Frequency oscillatory ventilation (HFOV). Initial experiences of a Neonatal Intensive Care Unit. Pediatr. (Asunción) [online]. 2010, vol.37, n.1, pp.36-41. ISSN 1683-9803.

Introduction: High-frequency oscillatory ventilation (HFOV) has become an alternative for various types of respiratory failure due to the failure of conventional mechanical ventilation. Objective: To assess the results of high-frequency oscillatory ventilation (HFOV) as resuscitative therapy for severe respiratory failure in newborns at a neonatal unit. Materials and Methods: A descriptive, analytic, observational study. Newborns were included with a diagnosis of severe respiratory insufficiency with an oxygenation index (OI) greater than 20 or a mean airway pressure (MAP) of 12 cm H2O. Results: During the study period lasting from March 2008 to March 2009, it was decided to use HFOV for 9 patients, of whom 2 were excluded due to death before use of HFOV therapy for unrelated causes. The remaining 7 patients had a mean age of 35 weeks, (range: 26-41 weeks), average weight of 2310 grams (range: 850-3810 grams), and an average OI on presentation of 33.6 with values of a maximum of 50 and a minimum of 1.5. Post-HFOV improvement greater than 20 mmHg PO2 was seen in 6 of 7 (90%) within the first hour. The survival ate was 43% (3 of 7). Conclusions: Although improved oxygenation, ventilation, and oxygenation index were seen after beginning HFOV, the survival rate of 43% (3 of 7) was not good

Palavras-chave : Newborns; high-frequency oscillatory ventilation; high-frequency ventilation; respiratory failure; respiratory insufficiency; oxygenation index.

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