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Pediatría (Asunción)

On-line version ISSN 1683-9803

Abstract

BATTAGLIA, Silvia; MOREL, Zoilo; BATISTA, Jorge  and  CENTURION, Yolanda. Incomplete Lupus Erythematosus Initially Manifesting as Autoimmune Thrombocytopenic Purpura in a Five-Month Old Infant. Pediatr. (Asunción) [online]. 2009, vol.36, n.3, pp.216-218. ISSN 1683-9803.

Idiopathic thrombocytopenic purpura is the most common form of thrombocytopenia during childhood, and usually appears without an associated systemic condition being identified.  Systemic Lupus Erythematosus is a chronic and multisystemic genetically-based autoimmune disease. Incomplete lupus erythematosus is considered to be present when the patient does not mean the criteria for systemic lupus erythematosus devised by the American College of Rheumatology (ACR) together with positive anti-nuclear antibody titer levels. We present the case of a five-month old female infant diagnosed with incomplete lupus erythematosus (as of current data) whose condition first manifested as autoimmune thrombocytopenic purpura and whose antinuclear and anticardiolipin antibodies titers were positive, but without detected effects on other systems. Since this test is considered to determine the existence of risk of later development of systemic lupus erythematosus, we suggest that antinuclear antibody testing should be requested in cases of autoimmune thrombocytopenic purpura and that adequate follow up be carried out to help avoid negative outcomes and improve patient prognosis.

Keywords : Autoimmune thrombocytopenic purpura; systemic lupus erythematosus; incomplete lupus erythematosus; antiphospholipid syndrome; child.

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