Introduction:

Diabetes mellitus is a prevalent disease with a high cost for public health. However, the lack of therapeutic compliance prevents that the morbidity and mortality associated with this pathology can be avoided.

Objective:

To determine the factors associated with the lack of adherence to treatment in patients with type 2 diabetes mellitus who attend the National Hospital of Itauguá in 2018.

Material and methods:

Observational, descriptive, prospective, longitudinal study, with analytical component, carried out in men and women older than 18 years with diagnosis of type 2 diabetes mellitus who attended the outpatient clinics of the National Hospital diabetes program in Itauguá in 2018. Adherence to treatment was determined with two validated scales that measured pharmacological (Morisky-Green) and non-pharmacological (IMEVID) adherence.

Results:

Three hundred and thirty eight patients were studied, 66% being female. The average age was 56 ± 7 years. The frequency of lack of adherence to treatment was 70% and the factors that were significantly associated were the presence of chronic complications (53%), pharmacological monotherapy (35%), presence of adverse drug effects (17%), time of evolution greater than ten years (16%) and poor doctor-patient relationship (16%).

Conclusions:

There is a high frequency of lack of adherence to treatment in patients with diabetes mellitus (70%). The presence of chronic complications and pharmacological monotherapy were the most frequently associated factors. This information will allow decision-making to help patients improve their therapeutic compliance.

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