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Revista del Instituto de Medicina Tropical
Print version ISSN 1996-3696
Abstract
ESCOBAR-SALINAS, Jorge Sebastián; DUARTE, Luis; SOBARZO-VYSOKOLAN, Patricia María Beatriz and FERREIRA SAMUDIO, María Leticia. Inflammatory biomarkers associated with mortality in patients with Sars-Cov-2 pneumonia. Rev. Inst. Med. Trop. [online]. 2022, vol.17, n.1, pp.35-43. ISSN 1996-3696. https://doi.org/10.18004/imt/2022.17.1.5.
Introduction
: SARS-CoV-2 infection produces laboratory abnormalities, which, although they are nonspecific, their values can be useful as prognostic markers.
Materials and methods
: Observational, analytical study of cases and controls, with a non-probabilistic sampling of consecutive cases from January to July 2021 in patients with SARS-CoV-2 infection at Hospital National.
Results
: A total of 237 patients (79 cases and 158 controls) were included, the age range was between 21 and 90 years (53.67±15.11). 66.7% were male. Statistically significant differences were found, with a tendency for deceased patients to present higher values of leukocytes (12,600 vs 9,672; p=0.001), CRP (15.40 vs 10.97; p=0.002), D-dimer (15,725 vs 3,714 ; p=0.004), Ferritin (1312 vs 1049; p=0.020), Troponin I (1.71 vs 1.87; p=0.003).
Conclusion
: The values of leukocytes, PCR, Dimer D, Ferritin, Troponin I, are significantly associated with mortality in this series of cases.
Keywords : SARS-CoV-2 infection; Pneumonia due to the New Coronavirus (2019-nCoV); COVID-19.
