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Medicina clínica y social
versión On-line ISSN 2521-2281
Resumen
MONTIEL-JAROLIN, Dora et al. Clinical and laboratory characteristics of adult ambulatory patients with Chikungunya at the National Hospital of Itauguá in Paraguay during the 2022-2023 epidemic. Med. clín. soc. [online]. 2023, vol.7, n.3, pp.161-167. ISSN 2521-2281. https://doi.org/10.52379/mcs.v7i3.322.
Introduction:
Acute infection by chikungunya produces a self-limited infection characterized mainly by high fever, arthralgia, arthritis, headache, myalgia and pruritic rash; a minority presents persistent symptoms that can evolve to chronicity.
Objective:
to describe the clinical and laboratory characteristics of adult ambulatory patients with chikungunya at a referral hospital during the 2022-2023 epidemic in Paraguay.
Method:
descriptive cross-sectional study of adult patients with chikungunya infection who consulted at the Hospital National de Itauguá between January-March 2023.
Results:
140 patients between 19 and 79 years old (mean age: 46.6 ± 13.6), 77.9% female and 89.3% from the Central department, were included. 72.9% of the patients were confirmed by RT-PCR and the rest by serology or epidemiological nexus. 48.6% had some comorbidity, 65% were in the acute phase, and the rest in the subacute phase (35%). The most frequent symptoms were polyarthralgia (96.4%); arthritis (98.6%), fever (95.7%), fatigue (100%), myalgia (96.4%), headache (82.9%), rash (95%). Gastrointestinal symptoms were less frequent such as; nausea (37%), vomiting (15.7%) and diarrhea (20%). Increased C-reactive protein (45.7%), leukopenia (23.6%), increased erythrocyte sedimentation rate (27.9%), and mild hepatic cytolysis (13.6%) were among the main laboratory findings. All patients were treated with paracetamol; 60.4% and 87.8% of the patients in the acute and subacute phase, respectively, received NSAIDs.
Discussion:
The combination of high fever and severe arthralgia can be considered the characteristic feature of chikungunya virus infection in this epidemic.
Palabras clave : Chikungunya; Arthralgia; arbovirus.