Abstract

TIRADO, Alberto Guevara. Correlation between Vitamin B12 and blood pressure in adults. Rev. cient. cienc. salud [online]. 2024, vol.6, e6139.  Epub May 27, 2024. ISSN 2664-2891.  https://doi.org/10.53732/rccsalud/2024.e6139.

Introduction. Vitamin B12 would affect blood pressure through hormonal and metabolic mechanisms. Objective. To analyze the relationship between vitamin B12 concentrations and blood pressure in adults. Materials and Methods. Observational, analytical, retrospective and cross-sectional study, from an open database made up of 4,154 people from a Mexican community served in a health facility. The variables were: sex, vitamin B12 and systolic blood pressure. The Chi-square test and student's t test were used. Results. the averages of vitamin B12 were lower in the presence of blood pressure equal to or greater than 130 mmHg (men: 217.12 pg/ml; women 204.51 pg/ml) compared to when it was compared with systolic blood pressure levels between 90 at 129 mmHg (men; 266.98 pg/ml; women: 205.18 og/ml). The correlation between vitamin B12 and blood pressure was low and negative in men (Rho=-0.022; p=0.018), women (Rho=-0.182; p<0.001) and in both groups together (Rho=-0.171; p< 0.001). Conclusion. Hypertensive adults have lower averages of vitamin B12 than normotensive adults. Likewise, vitamin B12 is weakly and negatively correlated with blood pressure. Normal levels of vitamin B12 with a tendency towards low limits could be one of the many factors that influence the early pathophysiology of arterial hypertension.

Keywords : vitamin B 12; arterial pressure; observational study; linear models; correlation of data.

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